Imipramine Release from Ca-Alginate Gel Beads.
نویسندگان
چکیده
منابع مشابه
SHOOT REGENERATION FROM SAFFRON PROTOPLASTS IMMOBILIZED IN Ca-ALGINATE BEADS
Saffron (Crocus sativus L.) protoplasts were isolated from the cells of a suspension culture or calli with a solution of Cellulase, Pectinase and Hemicellulase and embedded in Ca-alginate beads. They were cultured with or without nurse cells in MS medium supplemented with 2,4-D and 6-benzylaminopurine at 25°C. After several changes of medium, cell-clusters appeared on the surface of the Ca-algi...
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Calcium-induced alginate gel bead (Alg-Ca) coated with an alginate hydrolysate (Alg), e.g. the guluronic acid block (GB) was prepared and the model drug, hydrocortisone release profiles were investigated under simulated gastrointestinal conditions. Their molecular weights were one sixth or one tenth that of Alg and the diffraction patterns of the hydrolysates resembled that of Alg. The drug rel...
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Calcium-induced alginate gel beads (Alg-Ca) containing various polysaccharides, including an alginate hydrolysate, were prepared and the drug release profiles were investigated. Hydrocortisone (HC) was gradually released from Alg-Ca into the mimic gastric fluid, while in intestinal fluid, it was quickly released with the dissolution of Alg-Ca. However, with Alg-Ca containing 5% chitin (CT), dis...
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saffron (crocus sativus l.) protoplasts were isolated from the cells of a suspension culture or calli with a solution of cellulase, pectinase and hemicellulase and embedded in ca-alginate beads. they were cultured with or without nurse cells in ms medium supplemented with 2,4-d and 6-benzylaminopurine at 25°c. after several changes of medium, cell-clusters appeared on the surface of the ca-algi...
متن کاملEvaluation of tetrandrine sustained release calcium alginate gel beads in vitro and in vivo.
An approach for the preparation of tetrandrine sustained release calcium alginate gel beads was described. In vitro the release of tetrandrine from sustained release dosage forms went on a time of 12 hours which fitted non-Fickian diffusion with matrix erosion significantly. In vivo the plasma concentration of tetrandrine extended preparation given in dogs reached Cmax 2.67+/-0.69 microg/ml app...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1993
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.41.1475